What is generic Cialis? This is the first question one must ask before making any conclusions. Generic Cialis is a pharmaceutical copy of Cialis that is no different from the original branded medication. This means that Generic Cialis is cheaper than branded versions but made based on the same formula and with the same ingredients.
In order to understand how Cialis works, we need to know what Cialis is. In essence, this is a medication based on Tadalafil which is another phosphodiesterase type 5 inhibitor just like sildenafil which is the core ingredient of Viagra. Tadalafil is a one of the most efficient PDE5 inhibitors known to science and is used to treat various health issues related to arterial hypertension. At the same time, it is widely used to treat erectile dysfunction especially coupled with benign prostatic hyperplasia.
The Core Differences between Generic Cialis and Generic Viagra
One of the core differences between Generic Cialis and Generic Viagra is price. In the vast majority of cases, tadalafil based medications cost twice as much as sildenafil. The more sophisticated production process and arguably better effectiveness of tadalafil make its price higher than that of Viagra. The price difference is completely justified.
Many use a term “Weekend Pill” when referring to Cialis. The reason is that Tadalafil has a longer period of effective presence in the organism compared to other PDE5 inhibitors. The difference is quite substantial. For comparison, sildenafil half-life period in the body is roughly 5 hours at maximum. On the other hand, tadalafil lasts for up to 18 hours and has a persistent effect during this time span. Due to this difference and longer effectiveness, people refer to Cialis as a “weekend pill”.
Pharmacodynamics of the medication is similar to that of Viagra. The erection is achieved after increasing the amount of cGMP (cyclic guanosine monophosphate) which drastically changes the biochemistry and releases much more nitric oxide in order to make penile arteries and muscles nearby relaxed and ready for the blood stream. This allows blood to fill the vessels in Penis and erection occurs.
Tadalafil does not work without direct sexual stimulation. The whole process of erection is based on the instinctive response of penile tissues to direct stimulation.
All PDE5 inhibitors works alike and serve to the same purpose. As mentioned above, the main difference between Tadalafil and Sildenafil is the time of effect. Scientists worked for a long time to synthesize a PDE5 inhibitor that would last longer in the organism and Tadalafil is one of the most efficient findings so far.
The Impact of Tadalafil
The marketing team behind Viagra is a lucky one. Back then, the competition for Viagra was fairly limited and many other medications were highly ineffective with some direct competitors showing the success rate lesser than 40%. Sildenafil based medications showed an incredible 80% success rate and kept showing spectacular results in the period after marketing.
Cialis entered the market when it was occupied by branded Viagra. This is why many people have heard about Viagra, but may not even know about the very existence of Generic Cialis which is arguably even more effective than Viagra. The difference in effectiveness shows in how long the effect lasts. Viagra requires men to take several pills in case they plan sexual activities over the course of two or more days. In many cases, taking a single pill of generic Cialis may seal the deal.
Tadalafil definitely improved the situation in the market by creating more versatility both in terms of price and utility. Those people who need short-term solutions for their erectile dysfunction may choose Viagra as a cheaper option with a short-term effect. Seeking for a more powerful and more expensive solution will choose Cialis instead. This is a better market environment that allows men to choose the best option for their specific issues.
To follow through, here are the best offers on brand Cialis and Generic Cialis among Canadian and US online pharmacies:
- accessrx.com – $86.00 per pill (brand Cialis)
- kwikmed.com – $43.30 per pill (brand Cialis)
- canadadrugs.com – $24.40 per pill (brand Cialis)
- mycanadianpharmacypro.com – $1.43 per pill (generic Cialis)
- northwestpharmacy.com – $20 per pill and price for generic Cialis $9.5 per pill
As you can see, My Canadian Pharmacy actually offers one of the best offers on the market. Of course, you can pay over for the brand pill at Accessrx or Canadadrugs, if you still have trust issues with generics, but based on customer reviews, the quality of generic Cialis from My canadian pharmacy is just fine.
Generic Cialis is cheaper than branded versions and have the same effect. This made the medication more affordable and allowed more men to use it for treating erectile dysfunction.
Side effects and known issues with Generic Cialis
In essence, tadalafil is still another PDE5 inhibitor even if it lasts longer than other PDE5 inhibitors. This means that Cialis shares side effects and problems with sildenafil or vardenafil. After the marketing, the sample size of studies was drastically expanded. Over 8 million customers have tried Cialis after it was released worldwide and more than 15 thousand participants of preliminary tests were also carefully studied.
Most of the side effects are harmless and disappear after a few hours. These symptoms are common for PDE5 inhibitors and caused by the expansion of blood vessels caused by unexpectedly high rate of NO generation in the organism. This effect can be reduced by adjusting the intake of tadalafil. If certain side effects occur, reducing the dose is one of the most straight-forward and effective solutions.
The list of most commonly occurring side effects include discomfort in abdomen, aches in back, muscle pains, minor issues with digestion, and stuffy nose. Many symptoms have a very short lasting nature. However, muscle and back pains may occur later and last longer, up to 2 days. Note that many symptoms may be more frequent or harmful due to physiological specifics of individuals. For example, people with weaker vascular systems may suffer from a wider list of more severe side effects.
While the prescription for tadalafil is not required to make a purchase online, consulting a doctor is a good idea in order to ensure that you can take PDE5 inhibitors without any risk for your health.
One of the problems discovered during the after-marketing period was unexpected temporary hearing loss. This happened only several times and has a very small occurrence rate, but still needs to be taken into consideration when choosing the best medication for treating erectile dysfunction.
Tadalafil and other drugs
This issue is common for both tadalafil and sildenafil. As mentioned above, both generic Cialis and Viagra are essentially PDE5 inhibitors and thus share many disadvantages and advantages characteristic for this type of medications. One of the biggest concerns that should be on the mind of a person who wants to try out any PDE5 inhibitor is low blood pressure caused by the intake of tadalafil. The risk of hypotension is further increased with the intake of other supplementary sex drugs that are based on various organic nitrites. It is highly recommended to take nitrates in order to normalize the blood pressure.
There may be other issues with simultaneous intake of Generic Cialis with other drugs especially those that directly affect blood vessel system and blood circulation. Another important issue is that using PDE5 inhibitors without nitrates to neutralize their effect right after usage is a potential risk factor that should be considered by anyone who wants to treat erectile dysfunction with Generic Cialis.
Conclusion
In many ways, Generic Cialis is similar to Viagra. Both drugs are based on PDE5 inhibitors and work alike. However, tadalafil in Cialis is a long-lasting compound that has an arguably better effect compared to sildenafil in Viagra. Another important difference is the price since Generic Cialis usually priced higher than Generic Viagra. Ultimately, the choice between two drugs should be made based on individual specificities of the organism and personal preferences.