Grifulvin V belongs to the group of medicines called antifungals. It is used to treat fungus infections of the skin, hair, fingernails, and toenails. This medicine may be taken alone or used along with medicines that are applied to the skin for fungus infections.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For griseofulvin, the following should be considered:
Allergies-Tell your doctor if you have ever had any unusual or allergic reaction to penicillins, penicillamine (e.g., Cuprimine), or griseofulvin. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy-Griseofulvin should not be used during pregnancy. The birth of twins that were joined together has been reported, although rarely, in women who took griseofulvin during the first 3 months of pregnancy. In addition, studies in rats and dogs have shown that griseofulvin causes birth defects and other problems.
Breast-feeding-It is not known if griseofulvin is excreted in breast milk. However, griseofulvin has not been reported to cause problems in nursing babies.
Children – This medicine has been tested in a limited number of children 2 years of age or older. In effective doses, the medicine has not been shown to cause different side effects or problems than it does in adults.
Older adults – Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of griseofulvin in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.
Other medicines – Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking griseofulvin, it is especially important that your health care professional knows if you are taking any of the following:
* Anticoagulants (blood thinners)-Griseofulvin may decrease the effectiveness of anticoagulants in some patients
* Oral contraceptives (birth control pills) containing estrogen-Griseofulvin may decrease the effectiveness of birth control pills, which may result in breakthrough bleeding and unwanted pregnancies